Sitagliptin Repositioning in SARS-CoV-2: Effects on ACE-2, CD-26, and Inflammatory Cytokine Storms in the Lung.

Dastan, Farzaneh; Abedini, Atefeh; Shahabi, Shahram; Kiani, Arda; Saffaei, Ali; Zare, Ahad

Dastan, Farzaneh; Abedini, Atefeh; Shahabi, Shahram; Kiani, Arda; Saffaei, Ali; Zare, Ahad.

Afiliação

Dastan F; Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran AND Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. fz
Abedini A; Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. dr.abedini110@gmail.com.
Shahabi S; Department of Research and Development, SHC-Hyland's Inc., Los Angeles, California, U.S.A. sshahabi@hylands.com.
Kiani A; Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. ardakiani@yahoo.com.
Saffaei A; Student Research Committee, Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. alisaffaei.ss@gmail.com.
Zare A; Sarem Cell Research Center (SCRC), Sarem Women's Hospital, Tehran, Iran AND Department of Immunology, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. ahadzareee@gmail.com.

Iran J Allergy Asthma Immunol ; 19(S1): 10-12, 2020 May 17.

Article em En | MEDLINE | ID: mdl-32534505

Assuntos

Betacoronavirus/efeitos dos fármacos; Infecções por Coronavirus/tratamento farmacológico; Inibidores da Dipeptidil Peptidase IV/farmacologia; Reposicionamento de Medicamentos; Pneumonia Viral/tratamento farmacológico; Fosfato de Sitagliptina/farmacologia; Enzima de Conversão de Angiotensina 2; COVID-19; Infecções por Coronavirus/metabolismo; Citocinas/efeitos dos fármacos; Dipeptidil Peptidase 4/efeitos dos fármacos; Dipeptidil Peptidase 4/metabolismo; Humanos; Inflamação/tratamento farmacológico; Inflamação/virologia; Pulmão/efeitos dos fármacos; Pulmão/metabolismo; Pandemias; Peptidil Dipeptidase A/efeitos dos fármacos; Peptidil Dipeptidase A/metabolismo; Pneumonia Viral/metabolismo; SARS-CoV-2

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Inibidores da Dipeptidil Peptidase IV / Reposicionamento de Medicamentos / Fosfato de Sitagliptina / Betacoronavirus Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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