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Lethal Outcome of Leptospirosis in Southern Russia: Characterization of Leptospira Interrogans Isolated from a Deсeased Teenager.
Samoilov, Andrei E; Stoyanova, Nataliya A; Tokarevich, Nikolai K; Evengard, Birgitta; Zueva, Elena V; Panferova, Yulia A; Ostankova, Yulia V; Zueva, Elena B; Valutite, Diana E; Kovalev, Evgeniy V; Litovko, Anna R; Goncharov, Alexey U; Semenov, Alexandr V; Khafizov, Kamil; Dedkov, Vladimir G.
Afiliação
  • Samoilov AE; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Stoyanova NA; Central Research Institute for Epidemiology, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 111123 Moscow, Russia.
  • Tokarevich NK; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Evengard B; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Zueva EV; Department of Clinical Microbiology, Umeå University, 90187 Umeå, Sweden.
  • Panferova YA; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Ostankova YV; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Zueva EB; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Valutite DE; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Kovalev EV; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Litovko AR; Department of Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance in the Rostov Region, 344019 Rostov-on-Don, Russia.
  • Goncharov AU; Center for Hygiene and Epidemiology in the Rostov Region, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 344029 Rostov-on-Don, Russia.
  • Semenov AV; Center for Hygiene and Epidemiology in the Rostov Region, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 344029 Rostov-on-Don, Russia.
  • Khafizov K; Pasteur Institute, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 197101 Saint-Petersburg, Russia.
  • Dedkov VG; Central Research Institute for Epidemiology, Federal Service on Consumers' Rights Protection and Human Well-Being Surveillance, 111123 Moscow, Russia.
Article em En | MEDLINE | ID: mdl-32545855
ABSTRACT
This article describes a lethal case of leptospirosis that occurred in Southern Russia. The Leptospira strain was isolated and characterized using a microscopic agglutination test, MALDI-TOF mass spectrometry, targeted PCR, and high-throughput sequencing. We show that molecular and mass-spectrometry methods can be an alternative to conventional methods of leptospirosis diagnostics and Leptospira study, which require highly qualified staff and can be performed only at specialized laboratories. We also report the first whole genome of L. interrogans isolated in Russia.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leptospira / Leptospira interrogans / Leptospirose Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leptospira / Leptospira interrogans / Leptospirose Idioma: En Ano de publicação: 2020 Tipo de documento: Article