Silver Nanoparticle-Induced Apoptosis in ARPE-19 Cells Is Inhibited by <i>Toxoplasma gondii</i> Pre-Infection Through Suppression of NOX4-Dependent ROS Generation.

Quan, Juan-Hua; Gao, Fei Fei; Ismail, Hassan Ahmed Hassan Ahmed; Yuk, Jae-Min; Cha, Guang-Ho; Chu, Jia-Qi; Lee, Young-Ha

Silver Nanoparticle-Induced Apoptosis in ARPE-19 Cells Is Inhibited by Toxoplasma gondii Pre-Infection Through Suppression of NOX4-Dependent ROS Generation.

Quan, Juan-Hua; Gao, Fei Fei; Ismail, Hassan Ahmed Hassan Ahmed; Yuk, Jae-Min; Cha, Guang-Ho; Chu, Jia-Qi; Lee, Young-Ha.

Afiliação

Quan JH; Department of Gastroenterology, The Affiliated Hospital of Guangdong Medical University, Zhanjiang 524-001, People's Republic of China.
Gao FF; Department of Infection Biology and Department of Medical Science, Chungnam National University College of Medicine, Daejeon 301-131, Korea.
Ismail HAHA; Communicable and Non-Communicable Diseases Control Directorate, Federal Ministry of Health, Khartoum, Sudan.
Yuk JM; Department of Infection Biology and Department of Medical Science, Chungnam National University College of Medicine, Daejeon 301-131, Korea.
Cha GH; Department of Infection Biology and Department of Medical Science, Chungnam National University College of Medicine, Daejeon 301-131, Korea.
Chu JQ; Stem Cell Research and Cellular Therapy Center, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province 524-001, People's Republic of China.
Lee YH; Department of Infection Biology and Department of Medical Science, Chungnam National University College of Medicine, Daejeon 301-131, Korea.

Int J Nanomedicine ; 15: 3695-3716, 2020.

Article em En | MEDLINE | ID: mdl-32547023

Assuntos

Apoptose/efeitos dos fármacos; Nanopartículas Metálicas/química; NADPH Oxidase 4/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Epitélio Pigmentado da Retina/metabolismo; Epitélio Pigmentado da Retina/parasitologia; Prata/farmacologia; Toxoplasmose/patologia; Animais; Autofagia/efeitos dos fármacos; Linhagem Celular; Forma Celular/efeitos dos fármacos; Modelos Animais de Doenças; Fibroblastos/efeitos dos fármacos; Fibroblastos/parasitologia; Fase G1/efeitos dos fármacos; Humanos; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Masculino; Camundongos; Mitocôndrias/efeitos dos fármacos; Mitocôndrias/metabolismo; Modelos Biológicos; Fosforilação/efeitos dos fármacos

Palavras-chave

NADPH oxidase 4; Toxoplasma gondii; human retinal pigment epithelium; mitochondrial apoptosis; reactive oxygen species; silver nanoparticles

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prata / Toxoplasmose / Espécies Reativas de Oxigênio / Apoptose / Nanopartículas Metálicas / Epitélio Pigmentado da Retina / NADPH Oxidase 4 Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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