Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.

Lee, Yeunkum; Zhang, Yinhua; Kang, Hyojin; Bang, Geul; Kim, Yoonhee; Kang, Hyae Rim; Ma, Ruiying; Jin, Chunmei; Kim, Jin Young; Han, Kihoon

Lee, Yeunkum; Zhang, Yinhua; Kang, Hyojin; Bang, Geul; Kim, Yoonhee; Kang, Hyae Rim; Ma, Ruiying; Jin, Chunmei; Kim, Jin Young; Han, Kihoon.

Afiliação

Lee Y; Department of Neuroscience, College of Medicine, Korea University, Seoul, 02841, South Korea; Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, 02841, South Korea.
Zhang Y; Department of Neuroscience, College of Medicine, Korea University, Seoul, 02841, South Korea; Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, 02841, South Korea.
Kang H; Division of National Supercomputing, KISTI, Daejeon, 34141, South Korea.
Bang G; Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Ochang, 28119, South Korea; College of Pharmacy, Korea University, Sejong, 30019, South Korea.
Kim Y; Department of Neuroscience, College of Medicine, Korea University, Seoul, 02841, South Korea.
Kang HR; Department of Neuroscience, College of Medicine, Korea University, Seoul, 02841, South Korea; Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, 02841, South Korea.
Ma R; Department of Neuroscience, College of Medicine, Korea University, Seoul, 02841, South Korea.
Jin C; Department of Neuroscience, College of Medicine, Korea University, Seoul, 02841, South Korea; Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, 02841, South Korea.
Kim JY; Research Center for Bioconvergence Analysis, Korea Basic Science Institute, Ochang, 28119, South Korea. Electronic address: jinyoung@kbsi.re.kr.
Han K; Department of Neuroscience, College of Medicine, Korea University, Seoul, 02841, South Korea; Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, 02841, South Korea. Electronic address: neurohan@korea.ac.kr.

Biochem Biophys Res Commun ; 529(1): 1-6, 2020 08 13.

Article em En | MEDLINE | ID: mdl-32560809

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Epilepsia/metabolismo; Deficiência Intelectual/metabolismo; Prosencéfalo/metabolismo; Actinas/metabolismo; Proteínas Adaptadoras de Transdução de Sinal/genética; Animais; Animais Recém-Nascidos; Modelos Animais de Doenças; Epilepsia/genética; Variação Genética; Células HeLa; Humanos; Deficiência Intelectual/genética; Camundongos; Camundongos Transgênicos; Mapas de Interação de Proteínas; Proteínas de Ligação a RNA/metabolismo

Palavras-chave

CYFIP2; Interactome; Neonatal forebrain; RNA-binding protein; Stress granule

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Prosencéfalo / Proteínas Adaptadoras de Transdução de Sinal / Epilepsia / Deficiência Intelectual Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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