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Ovarian Solid Pseudopapillary Tumor Resembling Benign Hemorrhagic Cyst on Rapid Frozen Section.
Nguyen, Michelle T; Carter, Michael; Zhao, Zimin; Abidi, Alireza; Hodeib, Melissa.
Afiliação
  • Nguyen MT; Department of Obstetrics and Gynecology, Adventist Health White Memorial, Los Angeles, CA, USA.
  • Carter M; Department of Obstetrics and Gynecology, Kaiser Permanente Southern California, Riverside, CA 92505, USA.
  • Zhao Z; Department of Pathology, Kaiser Permanente Southern California, Riverside, CA 92505, USA.
  • Abidi A; Department of Gynecologic Oncology, Kaiser Permanente Southern California, Riverside, CA 92505, USA.
  • Hodeib M; Department of Gynecologic Oncology, Kaiser Permanente Southern California, Riverside, CA 92505, USA.
Case Rep Obstet Gynecol ; 2020: 6473630, 2020.
Article em En | MEDLINE | ID: mdl-32566338
ABSTRACT
Solid pseudopapillary tumors are rare, with the majority of described cases originating in the pancreas. To date, there are only 10 documented reports of primary ovarian solid pseudopapillary tumors. Here, we describe the case of a 24-year-old woman who presented with worsening pelvic pain and dysmenorrhea. Workup demonstrated a right ovarian solid mass on ultrasound and an elevated serum LDH, which raised concerns for dysgerminoma due to her relatively young age. Therefore, she was taken to the operating room and underwent laparoscopic right salpingo-oophorectomy. On initial rapid frozen section, her ovarian cyst had a grossly hemorrhagic appearance with multiple hemosiderin deposits noted microscopically, which suggested a benign hemorrhagic cyst. However, the final pathology was reported as solid pseudopapillary tumor based on several defining histologic characteristics. Most importantly, immunostaining was positive for ß-catenin and negative for E-cadherin. This report presents a brief review of the current literature on primary ovarian solid pseudopapillary tumors, including a discussion of expected prognosis after surgical resection, as well as a discussion of the role of immunohistochemistry (IHC) in differentiating ovarian neoplasms in young premenopausal women.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article