ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells.

Gao, Zeyun; Dlamini, Mongameli B; Ge, Hong; Jiang, Liping; Geng, Chengyan; Li, Qiujuan; Shi, Xiaoxia; Liu, Yong; Cao, Jun

Gao, Zeyun; Dlamini, Mongameli B; Ge, Hong; Jiang, Liping; Geng, Chengyan; Li, Qiujuan; Shi, Xiaoxia; Liu, Yong; Cao, Jun.

Afiliação

Gao Z; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian 116044, China.
Dlamini MB; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian 116044, China.
Ge H; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian 116044, China.
Jiang L; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian 116044, China.
Geng C; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian 116044, China.
Li Q; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian 116044, China.
Shi X; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian 116044, China.
Liu Y; School of Life Science and Medicine, Dalian University of Technology, Panjin 124221, China.
Cao J; Department of Occupational and Environmental Health, Dalian Medical University, No. 9 W. Lvshun South Road, Dalian 116044, China. Electronic address: caojunly@163.com.

Toxicol Lett ; 331: 178-187, 2020 Oct 01.

Article em En | MEDLINE | ID: mdl-32569804

Assuntos

Fator 4 Ativador da Transcrição/metabolismo; Apoptose/efeitos dos fármacos; Autofagia/efeitos dos fármacos; Cromo/toxicidade; Estresse do Retículo Endoplasmático/efeitos dos fármacos; Poluentes Ambientais/toxicidade; Glicólise/efeitos dos fármacos; Células A549; Fator 4 Ativador da Transcrição/genética; Apoptose/genética; Autofagia/genética; Estresse do Retículo Endoplasmático/genética; Técnicas de Silenciamento de Genes; Glicólise/genética; Humanos

Palavras-chave

ATF4; Apoptosis; Autophagy; Endoplasmic reticulum stress; Glycolysis; Potassium dichromate

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Cromo / Apoptose / Poluentes Ambientais / Fator 4 Ativador da Transcrição / Estresse do Retículo Endoplasmático / Glicólise Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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