Tight expression regulation of senataxin, linked to motor neuron disease and ataxia, is required to avert cell-cycle block and nucleolus disassembly.

Bennett, Craig L; Sopher, Bryce L; La Spada, Albert R

Bennett, Craig L; Sopher, Bryce L; La Spada, Albert R.

Afiliação

Bennett CL; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
Sopher BL; Department of Neurology, University of Washington Medical Center, Seattle, WA 98195, USA.
La Spada AR; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.

Heliyon ; 6(6): e04165, 2020 Jun.

Article em En | MEDLINE | ID: mdl-32577562

Palavras-chave

ALS4; Ataxia; Cell biology; Fibrillarin; Gene expression; Gene regulation; Genetics; Helicase; Infectious disease; Mutation; Neuroscience; Nucleolus; Senataxin

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article