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FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease.
Saevarsdottir, Saedis; Olafsdottir, Thorunn A; Ivarsdottir, Erna V; Halldorsson, Gisli H; Gunnarsdottir, Kristbjorg; Sigurdsson, Asgeir; Johannesson, Ari; Sigurdsson, Jon K; Juliusdottir, Thorhildur; Lund, Sigrun H; Arnthorsson, Asgeir O; Styrmisdottir, Edda L; Gudmundsson, Julius; Grondal, Gerdur M; Steinsson, Kristjan; Alfredsson, Lars; Askling, Johan; Benediktsson, Rafn; Bjarnason, Ragnar; Geirsson, Arni J; Gudbjornsson, Bjorn; Gudjonsson, Hallgrimur; Hjaltason, Haukur; Hreidarsson, Astradur B; Klareskog, Lars; Kockum, Ingrid; Kristjansdottir, Helga; Love, Thorvardur J; Ludviksson, Bjorn R; Olsson, Tomas; Onundarson, Pall T; Orvar, Kjartan B; Padyukov, Leonid; Sigurgeirsson, Bardur; Tragante, Vinicius; Bjarnadottir, Kristbjorg; Rafnar, Thorunn; Masson, Gisli; Sulem, Patrick; Gudbjartsson, Daniel F; Melsted, Pall; Thorleifsson, Gudmar; Norddahl, Gudmundur L; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Stefansson, Kari.
Afiliação
  • Saevarsdottir S; deCODE genetics/Amgen, Reykjavik, Iceland. saedis.saevarsdottir@decode.is.
  • Olafsdottir TA; Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden. saedis.saevarsdottir@decode.is.
  • Ivarsdottir EV; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. saedis.saevarsdottir@decode.is.
  • Halldorsson GH; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland. saedis.saevarsdottir@decode.is.
  • Gunnarsdottir K; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Sigurdsson A; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Johannesson A; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Sigurdsson JK; School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland.
  • Juliusdottir T; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Lund SH; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Arnthorsson AO; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Styrmisdottir EL; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Gudmundsson J; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Grondal GM; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Steinsson K; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Alfredsson L; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Askling J; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Benediktsson R; deCODE genetics/Amgen, Reykjavik, Iceland.
  • Bjarnason R; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Geirsson AJ; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Gudbjornsson B; Center for Rheumatology Research, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Gudjonsson H; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Hjaltason H; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Hreidarsson AB; Center for Rheumatology Research, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Klareskog L; The Icelandic Medical Center, Mjodd, Reykjavik, Iceland.
  • Kockum I; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Kristjansdottir H; Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
  • Love TJ; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Ludviksson BR; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Olsson T; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Onundarson PT; Children's Medical Center, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Orvar KB; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Padyukov L; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Sigurgeirsson B; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Tragante V; Center for Rheumatology Research, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Bjarnadottir K; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Rafnar T; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Masson G; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Sulem P; Department of Neurology, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Gudbjartsson DF; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Melsted P; Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Thorleifsson G; Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
  • Norddahl GL; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Thorsteinsdottir U; Center for Rheumatology Research, Landspitali, The National University Hospital of Iceland, Reykjavik, Iceland.
  • Jonsdottir I; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
  • Stefansson K; The Icelandic Medical Center, Mjodd, Reykjavik, Iceland.
Nature ; 584(7822): 619-623, 2020 08.
Article em En | MEDLINE | ID: mdl-32581359
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tireoidite Autoimune / Códon sem Sentido / Predisposição Genética para Doença / Tirosina Quinase 3 Semelhante a fms / Ligantes / Mutação Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tireoidite Autoimune / Códon sem Sentido / Predisposição Genética para Doença / Tirosina Quinase 3 Semelhante a fms / Ligantes / Mutação Idioma: En Ano de publicação: 2020 Tipo de documento: Article