A potential strategy for in-stent restenosis: Inhibition of migration and proliferation of vascular smooth muscle cells by Cu ion.

Zhang, Yuan; Wang, Xiaoyan; Ma, Zhiling; Bai, Bing; Liu, Jie; Yang, Lei; Qin, Gaowu; Zhang, Erlin

Zhang, Yuan; Wang, Xiaoyan; Ma, Zhiling; Bai, Bing; Liu, Jie; Yang, Lei; Qin, Gaowu; Zhang, Erlin.

Afiliação

Zhang Y; Key Lab. for Anisotropy and Texture of Materials, Education Ministry of China, School of Materials Science and Engineering, Northeastern University, Shenyang 110819, China.
Wang X; School of Metallurgy, Northeastern University, Shenyang 110819, China.
Ma Z; School of Material Science and Engineering, Jiamusi University, Jiamusi 154007, China.
Bai B; Department of Prosthodontics, School of Stomatology, China Medical University, Shenyang 110001, China.
Liu J; School of Material Science and Engineering, Jiamusi University, Jiamusi 154007, China.
Yang L; Key Lab. for Anisotropy and Texture of Materials, Education Ministry of China, School of Materials Science and Engineering, Northeastern University, Shenyang 110819, China.
Qin G; Key Lab. for Anisotropy and Texture of Materials, Education Ministry of China, School of Materials Science and Engineering, Northeastern University, Shenyang 110819, China.
Zhang E; Key Lab. for Anisotropy and Texture of Materials, Education Ministry of China, School of Materials Science and Engineering, Northeastern University, Shenyang 110819, China. Electronic address: zhangel@atm.neu.edu.cn.

Mater Sci Eng C Mater Biol Appl ; 115: 111090, 2020 Oct.

Article em En | MEDLINE | ID: mdl-32600694

Assuntos

Caspase 3/metabolismo; Cobre/farmacologia; Reestenose Coronária/prevenção & controle; Músculo Liso Vascular/citologia; Animais; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Cobre/química; Reestenose Coronária/etiologia; Reestenose Coronária/metabolismo; Relação Dose-Resposta a Droga; Stents Farmacológicos/efeitos adversos; Humanos; Modelos Biológicos; Músculo Liso Vascular/efeitos dos fármacos; Músculo Liso Vascular/metabolismo; Ratos; Regulação para Cima

Palavras-chave

In-stent restenosis (ISR); Migration; Proliferation; Rat aortic smooth muscle cells (RASMCs)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cobre / Reestenose Coronária / Caspase 3 / Músculo Liso Vascular Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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