A Prospective, Split-Face, Randomized Study Comparing Picosecond to Q-Switched Nd: YAG Laser for Treatment of Epidermal and Dermal Pigmented Lesions in Asians.
Dermatol Surg
; 46(12): 1671-1675, 2020 12.
Article
em En
| MEDLINE
| ID: mdl-32604235
ABSTRACT
BACKGROUND:
Whether picosecond lasers outperform Q-switched lasers in treating pigmented lesions has not been clearly evaluated.OBJECTIVE:
To compare the efficacy and safety of picosecond and Q-switched lasers in treating epidermal and dermal pigmented lesions in Asians.METHODS:
Eight subjects with lentigines and 6 subjects with acquired bilateral nevus of Ota-like macules were enrolled. Subjects was randomly treated with a picosecond laser on one side of the face and a Q-switched laser on the other side. Subjective assessments on pigment clearance, and adverse effect were obtained at Weeks 0, 4, 12, and 24 after the final treatment.RESULTS:
Clinical improvement differed between the 2 laser systems at Week 4 (p = .034), Week 12 (p = .039), and Week 24 (p = .027), with 85.7% of picosecond and 57.2% of Q-switched laser sites showing >50% improvement at 6 months. There was no significant difference in the incidence of side effect and healing time, but picosecond laser was significantly associated with a lower treatment discomfort (p = .05).CONCLUSION:
The picosecond laser seems to be more effective and better tolerated than Q-switched laser for the treatment of pigmented lesions in Asians.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Nevo de Ota
/
Terapia com Luz de Baixa Intensidade
/
Lasers de Estado Sólido
/
Lentigo
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article