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Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti-PD-1 antibody in patients with mesothelioma and mouse tumor models.
Jiang, Qun; Ghafoor, Azam; Mian, Idrees; Rathkey, Daniel; Thomas, Anish; Alewine, Christine; Sengupta, Manjistha; Ahlman, Mark A; Zhang, Jingli; Morrow, Betsy; Steinberg, Seth M; Pastan, Ira; Hassan, Raffit.
Afiliação
  • Jiang Q; Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  • Ghafoor A; Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  • Mian I; Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  • Rathkey D; Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  • Thomas A; Developmental Therapeutics Branch, CCR, NCI, NIH, Bethesda, MD 20892, USA.
  • Alewine C; Laboratory of Molecular Biology, CCR, NCI, NIH, Bethesda, MD 20892, USA.
  • Sengupta M; Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  • Ahlman MA; Department of Radiology and Imaging Sciences, Clinical Center, NIH, Bethesda, MD 20892, USA.
  • Zhang J; Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  • Morrow B; Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
  • Steinberg SM; Biostatistics and Data Management Section, NCI, NIH, Bethesda, MD 20892, USA.
  • Pastan I; Laboratory of Molecular Biology, CCR, NCI, NIH, Bethesda, MD 20892, USA.
  • Hassan R; Thoracic and GI Malignancies Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892, USA. hassanr@mail.nih.gov.
Sci Transl Med ; 12(550)2020 07 01.
Article em En | MEDLINE | ID: mdl-32611684
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunotoxinas / Neoplasias Pulmonares / Mesotelioma Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunotoxinas / Neoplasias Pulmonares / Mesotelioma Idioma: En Ano de publicação: 2020 Tipo de documento: Article