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The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis.
Sheng, Yi-Hua; Leu, Wohn-Jenn; Chen, Ching-Nung; Hsu, Jui-Ling; Liu, Ying-Tung; Hsu, Lih-Ching; Hou, Duen-Ren; Guh, Jih-Hwa.
Afiliação
  • Sheng YH; School of Pharmacy, National Taiwan University, No.33, Linsen S. Rd., Zhongzheng Dist., Taipei 100, Taiwan.
  • Leu WJ; School of Pharmacy, National Taiwan University, No.33, Linsen S. Rd., Zhongzheng Dist., Taipei 100, Taiwan.
  • Chen CN; Department of Chemistry, National Central University, No. 300 Jhong-Da Road, Jhong-li, Taoyuan 32001, Taiwan.
  • Hsu JL; School of Pharmacy, National Taiwan University, No.33, Linsen S. Rd., Zhongzheng Dist., Taipei 100, Taiwan.
  • Liu YT; Department of Pharmacy, New Taipei Municipal TuCheng Hospital, Chang Gung Memorial Hospital, New Taipei City 236, Taiwan.
  • Hsu LC; School of Pharmacy, National Taiwan University, No.33, Linsen S. Rd., Zhongzheng Dist., Taipei 100, Taiwan.
  • Hou DR; School of Pharmacy, National Taiwan University, No.33, Linsen S. Rd., Zhongzheng Dist., Taipei 100, Taiwan.
  • Guh JH; Department of Chemistry, National Central University, No. 300 Jhong-Da Road, Jhong-li, Taoyuan 32001, Taiwan.
Molecules ; 25(12)2020 Jun 25.
Article em En | MEDLINE | ID: mdl-32630532

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pironas / Apoptose / Estresse Oxidativo / Ciclopropanos / Proteínas Quinases S6 Ribossômicas 70-kDa / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Pontos de Checagem da Fase G1 do Ciclo Celular / Neoplasias de Próstata Resistentes à Castração Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pironas / Apoptose / Estresse Oxidativo / Ciclopropanos / Proteínas Quinases S6 Ribossômicas 70-kDa / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Pontos de Checagem da Fase G1 do Ciclo Celular / Neoplasias de Próstata Resistentes à Castração Idioma: En Ano de publicação: 2020 Tipo de documento: Article