Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture.

Gulen, Burak; Rosselin, Marie; Fauser, Joel; Albers, Michael F; Pett, Christian; Krisp, Christoph; Pogenberg, Vivian; Schlüter, Hartmut; Hedberg, Christian; Itzen, Aymelt

Gulen, Burak; Rosselin, Marie; Fauser, Joel; Albers, Michael F; Pett, Christian; Krisp, Christoph; Pogenberg, Vivian; Schlüter, Hartmut; Hedberg, Christian; Itzen, Aymelt.

Afiliação

Gulen B; Center for Integrated Protein Science Munich (CIPSM), Department of Chemistry, Technical University of Munich, Garching, Germany.
Rosselin M; Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Fauser J; Chemical Biology Center (KBC), Institute of Chemistry, Umeå University, Umeå, Sweden.
Albers MF; Center for Integrated Protein Science Munich (CIPSM), Department of Chemistry, Technical University of Munich, Garching, Germany.
Pett C; Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Krisp C; Chemical Biology Center (KBC), Institute of Chemistry, Umeå University, Umeå, Sweden.
Pogenberg V; Chemical Biology Center (KBC), Institute of Chemistry, Umeå University, Umeå, Sweden.
Schlüter H; Clinical Chemistry and Laboratory Medicine, Mass Spectrometric Proteomics, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Hedberg C; Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Itzen A; Clinical Chemistry and Laboratory Medicine, Mass Spectrometric Proteomics, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.

Nat Chem ; 12(8): 732-739, 2020 08.

Article em En | MEDLINE | ID: mdl-32632184

Assuntos

Proteínas de Bactérias/metabolismo; Proteínas de Membrana/metabolismo; Nucleotidiltransferases/metabolismo; Monofosfato de Adenosina/metabolismo; Sequência de Aminoácidos; Proteínas de Bactérias/química; Proteínas de Bactérias/genética; Bartonella/metabolismo; Biocatálise; Cristalografia por Raios X; Células HeLa; Humanos; Proteínas de Membrana/química; Nucleotidiltransferases/química; Pasteurellaceae/metabolismo; Processamento de Proteína Pós-Traducional; Estrutura Terciária de Proteína; Alinhamento de Sequência; Especificidade por Substrato; Proteína cdc42 de Ligação ao GTP/genética; Proteína cdc42 de Ligação ao GTP/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Proteínas de Membrana / Nucleotidiltransferases Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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