Eco-evolutionary dynamics of nested Darwinian populations and the emergence of community-level heredity.
Elife
; 92020 07 07.
Article
em En
| MEDLINE
| ID: mdl-32633717
ABSTRACT
Interactions among microbial cells can generate new chemistries and functions, but exploitation requires establishment of communities that reliably recapitulate community-level phenotypes. Using mechanistic mathematical models, we show how simple manipulations to population structure can exogenously impose Darwinian-like properties on communities. Such scaffolding causes communities to participate directly in the process of evolution by natural selection and drives the evolution of cell-level interactions to the point where, despite underlying stochasticity, derived communities give rise to offspring communities that faithfully re-establish parental phenotype. The mechanism is akin to a developmental process (developmental correction) that arises from density-dependent interactions among cells. Knowledge of ecological factors affecting evolution of developmental correction has implications for understanding the evolutionary origin of major egalitarian transitions, symbioses, and for top-down engineering of microbial communities.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Hereditariedade
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Evolução Biológica
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Microbiota
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Modelos Genéticos
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article