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Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non-Small Cell Lung Cancer.
Li, Fei; Ng, Wai-Lung; Luster, Troy A; Hu, Hai; Sviderskiy, Vladislav O; Dowling, Catríona M; Hollinshead, Kate E R; Zouitine, Paula; Zhang, Hua; Huang, Qingyuan; Ranieri, Michela; Wang, Wei; Fang, Zhaoyuan; Chen, Ting; Deng, Jiehui; Zhao, Kai; So, Hon-Cheong; Khodadadi-Jamayran, Alireza; Xu, Mousheng; Karatza, Angeliki; Pyon, Val; Li, Shuai; Pan, Yuanwang; Labbe, Kristen; Almonte, Christina; Poirier, John T; Miller, George; Possemato, Richard; Qi, Jun; Wong, Kwok-Kin.
Afiliação
  • Li F; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Ng WL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Luster TA; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Hu H; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Sviderskiy VO; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Dowling CM; Department of Pathology, New York University School of Medicine, New York, New York.
  • Hollinshead KER; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Zouitine P; Department of Radiation Oncology, Perlmutter Cancer Center, New York University School of Medicine, New York, New York.
  • Zhang H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Huang Q; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Ranieri M; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Wang W; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Fang Z; S. Arthur Localio Laboratory, Department of Surgery, New York University School of Medicine, New York, New York.
  • Chen T; State Key Laboratory of Cell Biology, Innovation Center for Cell Signaling Network, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
  • Deng J; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Zhao K; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • So HC; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.
  • Khodadadi-Jamayran A; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.
  • Xu M; Department of Psychiatry, The Chinese University of Hong Kong, Sha Tin, Hong Kong SAR, China.
  • Karatza A; Applied Bioinformatics Laboratories and Genome Technology Center, Division of Advanced Research Technologies, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Pyon V; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Li S; Department of Medicine, Harvard Medical School, Boston, Massachusetts.
  • Pan Y; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Labbe K; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Almonte C; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Poirier JT; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Miller G; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Possemato R; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Qi J; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, NYU Langone Health, New York, New York.
  • Wong KK; S. Arthur Localio Laboratory, Department of Surgery, New York University School of Medicine, New York, New York.
Cancer Res ; 80(17): 3556-3567, 2020 09 01.
Article em En | MEDLINE | ID: mdl-32646968
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Técnicas Genéticas / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Técnicas Genéticas / Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Idioma: En Ano de publicação: 2020 Tipo de documento: Article