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Clearance of therapy-induced senescent tumor cells by the senolytic ABT-263 via interference with BCL-XL -BAX interaction.
Saleh, Tareq; Carpenter, Valerie J; Tyutyunyk-Massey, Liliya; Murray, Graeme; Leverson, Joel D; Souers, Andrew J; Alotaibi, Moureq R; Faber, Anthony C; Reed, Jason; Harada, Hisashi; Gewirtz, David A.
Afiliação
  • Saleh T; Department of Basic Medical Sciences, Faculty of Medicine, The Hashemite University, Zarqa, Jordan.
  • Carpenter VJ; Departments of Pharmacology & Toxicology, School of Medicine, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA.
  • Tyutyunyk-Massey L; Departments of Pharmacology & Toxicology, School of Medicine, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA.
  • Murray G; Departments of Pharmacology & Toxicology, School of Medicine, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA.
  • Leverson JD; Department of Physics, Virginia Commonwealth University, Richmond, VA, USA.
  • Souers AJ; AbbVie, North Chicago, IL, USA.
  • Alotaibi MR; AbbVie, North Chicago, IL, USA.
  • Faber AC; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
  • Reed J; Philips Institute for Oral Health Research, School of Dentistry, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA.
  • Harada H; Department of Physics, Virginia Commonwealth University, Richmond, VA, USA.
  • Gewirtz DA; Philips Institute for Oral Health Research, School of Dentistry, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA.
Mol Oncol ; 14(10): 2504-2519, 2020 10.
Article em En | MEDLINE | ID: mdl-32652830
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Senescência Celular / Proteína X Associada a bcl-2 / Proteína bcl-X / Compostos de Anilina Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Senescência Celular / Proteína X Associada a bcl-2 / Proteína bcl-X / Compostos de Anilina Idioma: En Ano de publicação: 2020 Tipo de documento: Article