Characterization of glutathione proteome in CHO cells and its relationship with productivity and cholesterol synthesis.

Chevallier, Valentine; Schoof, Erwin M; Malphettes, Laetitia; Andersen, Mikael R; Workman, Christopher T

Chevallier, Valentine; Schoof, Erwin M; Malphettes, Laetitia; Andersen, Mikael R; Workman, Christopher T.

Afiliação

Chevallier V; Upstream Process Sciences, UCB Nordic A/S, Copenhagen, Denmark.
Schoof EM; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Malphettes L; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.
Andersen MR; Upstream Process Sciences, UCB Pharma SA, Braine l'Alleud, Belgium.
Workman CT; Department of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.

Biotechnol Bioeng ; 117(11): 3448-3458, 2020 11.

Article em En | MEDLINE | ID: mdl-32662871

Assuntos

Butionina Sulfoximina/metabolismo; Colesterol/metabolismo; Glutationa/metabolismo; Proteoma/metabolismo; Animais; Células CHO/metabolismo; Cricetulus; Proteoma/análise; Proteômica

Palavras-chave

CHO cells; buthionine sulfoximine; cholesterol; glutathione; proteomics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Butionina Sulfoximina / Proteoma / Glutationa Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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