Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as &#8710;9-tetrahydrocannabinol to pigs.

Schaefer, Nadine; Nordmeier, Frederike; Kröll, Ann-Katrin; Körbel, Christina; Laschke, Matthias W; Menger, Michael D; Maurer, Hans H; Meyer, Markus R; Schmidt, Peter H

Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigs.

Schaefer, Nadine; Nordmeier, Frederike; Kröll, Ann-Katrin; Körbel, Christina; Laschke, Matthias W; Menger, Michael D; Maurer, Hans H; Meyer, Markus R; Schmidt, Peter H.

Afiliação

Schaefer N; Institute of Legal Medicine, Saarland University, Building 49.1, 66421, Homburg, Germany. nadine.schaefer@uks.eu.
Nordmeier F; Institute of Legal Medicine, Saarland University, Building 49.1, 66421, Homburg, Germany.
Kröll AK; Institute of Legal Medicine, Saarland University, Building 49.1, 66421, Homburg, Germany.
Körbel C; Institute for Clinical and Experimental Surgery, Saarland University, Building 65/66, 66421, Homburg, Germany.
Laschke MW; Institute for Clinical and Experimental Surgery, Saarland University, Building 65/66, 66421, Homburg, Germany.
Menger MD; Institute for Clinical and Experimental Surgery, Saarland University, Building 65/66, 66421, Homburg, Germany.
Maurer HH; Department of Experimental and Clinical Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Building 46, 66421, Homburg, Germany.
Meyer MR; Department of Experimental and Clinical Toxicology, Center for Molecular Signaling (PZMS), Saarland University, Building 46, 66421, Homburg, Germany.
Schmidt PH; Institute of Legal Medicine, Saarland University, Building 49.1, 66421, Homburg, Germany.

Arch Toxicol ; 94(10): 3421-3431, 2020 10.

Article em En | MEDLINE | ID: mdl-32666126

Assuntos

Tecido Adiposo/metabolismo; Canabinoides/análise; Canabinoides/metabolismo; Animais; Cromatografia Líquida; Dronabinol/análise; Dronabinol/metabolismo; Indóis/análise; Indóis/metabolismo; Pulmão/metabolismo; Masculino; Naftalenos/análise; Naftalenos/metabolismo; Absorção pelo Trato Respiratório; Manejo de Espécimes; Suínos; Espectrometria de Massas em Tandem; Fatores de Tempo

Palavras-chave

Adipose tissue, postmortem redistribution; Pigs; Pulmonary administration; Synthetic cannabinoids; Tetrahydrocannabinol

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canabinoides / Tecido Adiposo Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canabinoides / Tecido Adiposo Idioma: En Ano de publicação: 2020 Tipo de documento: Article