Increasing endogenous activity of NMDARs on GABAergic neurons increases inhibition, alters sensory processing and prevents noise-induced tinnitus.

Deng, Di; Masri, Samer; Yao, Lulu; Ma, Xiaoyan; Cao, Xuebing; Yang, Sungchil; Bao, Shaowen; Zhou, Qiang

Deng, Di; Masri, Samer; Yao, Lulu; Ma, Xiaoyan; Cao, Xuebing; Yang, Sungchil; Bao, Shaowen; Zhou, Qiang.

Afiliação

Deng D; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Masri S; Department of Physiology, University of Arizona, Tucson, AZ, 85724, USA.
Yao L; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Ma X; South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, China.
Cao X; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Yang S; School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Bao S; Department of Biomedical Sciences, City University of Hong Kong, Kowloon, Hong Kong.
Zhou Q; Department of Physiology, University of Arizona, Tucson, AZ, 85724, USA.

Sci Rep ; 10(1): 11969, 2020 07 20.

Article em En | MEDLINE | ID: mdl-32686710

Assuntos

Neurônios GABAérgicos/metabolismo; Inibição Neural/fisiologia; Ruído; Receptores de N-Metil-D-Aspartato/metabolismo; Sensação; Zumbido/metabolismo; Zumbido/fisiopatologia; Potenciais de Ação; Animais; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Parvalbuminas/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sensação / Zumbido / Receptores de N-Metil-D-Aspartato / Neurônios GABAérgicos / Inibição Neural / Ruído Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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