Microfluidic confinement enhances phenotype and function of hepatocyte spheroids.

Choi, Jong Hoon; Loarca, Lorena; De Hoyos-Vega, Jose M; Dadgar, Neda; Loutherback, Kevin; Shah, Vijay H; Stybayeva, Gulnaz; Revzin, Alexander

Choi, Jong Hoon; Loarca, Lorena; De Hoyos-Vega, Jose M; Dadgar, Neda; Loutherback, Kevin; Shah, Vijay H; Stybayeva, Gulnaz; Revzin, Alexander.

Afiliação

Choi JH; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
Loarca L; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
De Hoyos-Vega JM; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
Dadgar N; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
Loutherback K; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Shah VH; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
Stybayeva G; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
Revzin A; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.

Am J Physiol Cell Physiol ; 319(3): C552-C560, 2020 09 01.

Article em En | MEDLINE | ID: mdl-32697600

Assuntos

Hepatócitos/metabolismo; Microfluídica; Animais; Sobrevivência Celular; Células Cultivadas; Técnicas de Cocultura/métodos; Microfluídica/métodos; Fenótipo; Esferoides Celulares/metabolismo

Palavras-chave

alcohol injury; hepatocyte spheroids; microfluidic cultures

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatócitos / Microfluídica Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hepatócitos / Microfluídica Idioma: En Ano de publicação: 2020 Tipo de documento: Article