The effect of dexmedetomidine and remifentanil on the postoperative sore throat after thyroidectomy.
Medicine (Baltimore)
; 99(29): e21060, 2020 Jul 17.
Article
em En
| MEDLINE
| ID: mdl-32702848
ABSTRACT
BACKGROUND:
Postoperative sore throat (POST) is an important concern in surgical patients undergoing endotracheal intubation. Its prevalence after thyroidectomy is up to 80%. The current study aimed to assess the effect of dexmedetomidine and remifentanil on postoperative sore throat.METHODS:
Seventy-four patients who underwent thyroidectomy were randomized to receive either dexmedetomidine (group D) or remifentanil (group R). At anesthesia induction, group D received dexmedetomidine 1âµg/kg over 10âminutes, followed by continuous dexmedetomidine infusion at 0.3 to 0.6âµg/kg/hour during surgery. Group R received remifentanil of 3 to 4âng/ml during induction, followed by 1.5 to 2.5âng/ml remifentanil infusion during surgery. POST at rest and swallowing was assessed during the first 24âhours in serial time periods (0-1, 1-6, and 6-24âhours). Hoarseness and postoperative pain score were also assessed.RESULTS:
POST incidence at rest (0-1, 1-6, and 6-24âhours) and swallowing (1-6 and 6-24âhours) was lower in group D than in group R. POST severity was significantly lower in group D than in group R during each time period. The incidence of postoperative hoarseness was also lower in group D than in group R at 1 to 6 and 6 to 24âhours. The postoperative pain score was lower in group D than in group R during each time period.CONCLUSION:
Intraoperative dexmedetomidine infusion reduced the incidence and severity of POST for 24âhours after thyroidectomy.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Período Pós-Operatório
/
Tireoidectomia
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Faringite
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Dexmedetomidina
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Remifentanil
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article