Drebrin is induced during myofibroblast differentiation and enhances the production of fibrosis-related genes.

Hironaka, Takanori; Ueno, Tomoyuki; Mae, Kyosuke; Yoshimura, Chikashi; Morinaga, Takumi; Horii, Yuma; Nagasaka, Akiomi; Kurose, Hitoshi; Nakaya, Michio

Hironaka, Takanori; Ueno, Tomoyuki; Mae, Kyosuke; Yoshimura, Chikashi; Morinaga, Takumi; Horii, Yuma; Nagasaka, Akiomi; Kurose, Hitoshi; Nakaya, Michio.

Afiliação

Hironaka T; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Ueno T; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Mae K; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Yoshimura C; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Morinaga T; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Horii Y; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Nagasaka A; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Kurose H; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
Nakaya M; Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan. Electronic address: nakaya@phar.kyushu-u.ac.jp.

Biochem Biophys Res Commun ; 529(2): 224-230, 2020 08 20.

Article em En | MEDLINE | ID: mdl-32703415

Assuntos

Pulmão/patologia; Miocárdio/patologia; Miofibroblastos/patologia; Neuropeptídeos/genética; Animais; Diferenciação Celular; Células Cultivadas; Fibrose; Pulmão/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Miocárdio/metabolismo; Miofibroblastos/metabolismo; Células NIH 3T3; Fibrose Pulmonar/genética; Fibrose Pulmonar/patologia; Regulação para Cima

Palavras-chave

Actin cytoskeleton; Drebrin; Heart; Lung; Myofibroblast; TGF-ß

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neuropeptídeos / Miofibroblastos / Pulmão / Miocárdio Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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