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p63 uses a switch-like mechanism to set the threshold for induction of apoptosis.
Gebel, Jakob; Tuppi, Marcel; Chaikuad, Apirat; Hötte, Katharina; Schröder, Martin; Schulz, Laura; Löhr, Frank; Gutfreund, Niklas; Finke, Franziska; Henrich, Erik; Mezhyrova, Julija; Lehnert, Ralf; Pampaloni, Francesco; Hummer, Gerhard; Stelzer, Ernst H K; Knapp, Stefan; Dötsch, Volker.
Afiliação
  • Gebel J; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance and Cluster of Excellence Macromolecular Complexes (CEF), Goethe University, Frankfurt am Main, Germany.
  • Tuppi M; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance and Cluster of Excellence Macromolecular Complexes (CEF), Goethe University, Frankfurt am Main, Germany. marcel.tuppi@crick.ac.uk.
  • Chaikuad A; The Francis Crick Institute, London, UK. marcel.tuppi@crick.ac.uk.
  • Hötte K; Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt am Main, Germany.
  • Schröder M; Physikalische Biologie, Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University, Frankfurt am Main, Germany.
  • Schulz L; Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt am Main, Germany.
  • Löhr F; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.
  • Gutfreund N; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance and Cluster of Excellence Macromolecular Complexes (CEF), Goethe University, Frankfurt am Main, Germany.
  • Finke F; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance and Cluster of Excellence Macromolecular Complexes (CEF), Goethe University, Frankfurt am Main, Germany.
  • Henrich E; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance and Cluster of Excellence Macromolecular Complexes (CEF), Goethe University, Frankfurt am Main, Germany.
  • Mezhyrova J; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance and Cluster of Excellence Macromolecular Complexes (CEF), Goethe University, Frankfurt am Main, Germany.
  • Lehnert R; Institute of Biophysical Chemistry and Center for Biomolecular Magnetic Resonance and Cluster of Excellence Macromolecular Complexes (CEF), Goethe University, Frankfurt am Main, Germany.
  • Pampaloni F; Mathezentrum, Goethe University, Frankfurt am Main, Germany.
  • Hummer G; Physikalische Biologie, Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University, Frankfurt am Main, Germany.
  • Stelzer EHK; Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.
  • Knapp S; Institute of Biophysics, Goethe University, Frankfurt am Main, Germany.
  • Dötsch V; Physikalische Biologie, Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University, Frankfurt am Main, Germany.
Nat Chem Biol ; 16(10): 1078-1086, 2020 10.
Article em En | MEDLINE | ID: mdl-32719556
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Apoptose / Proteínas Supressoras de Tumor Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Apoptose / Proteínas Supressoras de Tumor Idioma: En Ano de publicação: 2020 Tipo de documento: Article