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KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements.
Au, Yan Zi; Gu, Muxin; De Braekeleer, Etienne; Gozdecka, Malgorzata; Aspris, Demetrios; Tarumoto, Yusuke; Cooper, Jonathan; Yu, Jason; Ong, Swee Hoe; Chen, Xi; Tzelepis, Konstantinos; Huntly, Brian J P; Vassiliou, George; Yusa, Kosuke.
Afiliação
  • Au YZ; Stem Cell Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • Gu M; Haematological Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • De Braekeleer E; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Gozdecka M; Haematological Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • Aspris D; Haematological Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • Tarumoto Y; Haematological Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • Cooper J; Wellcome Trust-MRC Stem Cell Institute, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.
  • Yu J; Haematological Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • Ong SH; Stem Cell Genetics, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
  • Chen X; Haematological Cancer Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • Tzelepis K; Stem Cell Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • Huntly BJP; Department of Cell Biology, The Francis Crick Institute, London, UK.
  • Vassiliou G; Stem Cell Genetics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
  • Yusa K; Gene Expression Genomics, Wellcome Sanger Institute, Hinxton, Cambridge, UK.
Leukemia ; 35(4): 1012-1022, 2021 04.
Article em En | MEDLINE | ID: mdl-32764680
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rearranjo Gênico / Leucemia Mieloide Aguda / Histona-Lisina N-Metiltransferase / Predisposição Genética para Doença / Histona Acetiltransferases / Proteína de Leucina Linfoide-Mieloide Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Rearranjo Gênico / Leucemia Mieloide Aguda / Histona-Lisina N-Metiltransferase / Predisposição Genética para Doença / Histona Acetiltransferases / Proteína de Leucina Linfoide-Mieloide Idioma: En Ano de publicação: 2021 Tipo de documento: Article