Estimation of Natural Selection and Allele Age from Time Series Allele Frequency Data Using a Novel Likelihood-Based Approach.

He, Zhangyi; Dai, Xiaoyang; Beaumont, Mark; Yu, Feng

He, Zhangyi; Dai, Xiaoyang; Beaumont, Mark; Yu, Feng.

Afiliação

He Z; Department of Statistics, University of Oxford, OX1 3LB, United Kingdom z.he@imperial.ac.uk feng.yu@bristol.ac.uk.
Dai X; School of Biological Sciences, University of Bristol, BS8 1TQ, United Kingdom.
Beaumont M; School of Biological Sciences, University of Bristol, BS8 1TQ, United Kingdom.
Yu F; School of Mathematics, University of Bristol, BS8 1UG, United Kingdom z.he@imperial.ac.uk feng.yu@bristol.ac.uk.

Genetics ; 216(2): 463-480, 2020 10.

Article em En | MEDLINE | ID: mdl-32769100

Assuntos

Frequência do Gene; Modelos Genéticos; Seleção Genética; Animais; DNA Antigo; Diploide; Humanos; Funções Verossimilhança; Cadeias de Markov

Palavras-chave

allele age; conditioned Wright-Fisher diffusion; hidden Markov model; maximum likelihood estimation; natural selection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Seleção Genética / Frequência do Gene / Modelos Genéticos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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