MYB-like transcription factor NoPSR1 is crucial for membrane lipid remodeling under phosphate starvation in the oleaginous microalga Nannochloropsis oceanica.
FEBS Lett
; 594(20): 3384-3394, 2020 10.
Article
em En
| MEDLINE
| ID: mdl-32770739
ABSTRACT
Membrane lipid remodeling under phosphate (Pi) limitation, a process that replaces structural membrane phospholipids with nonphosphorus lipids, is a widely observed adaptive response in plants and algae. Here, we identified the transcription factor phosphorus starvation response 1 (NoPSR1) as an indispensable player for regulating membrane lipid conversion during Pi starvation in the microalga Nannochloropsis oceanica. Knocking out NoPSR1 scarcely perturbed membrane lipid composition under Pi-sufficient conditions but significantly impaired dynamic alteration in membrane lipids during Pi starvation. In contrast, the absence of NoPSR1 led to no obvious change in cell proliferation or storage lipid accumulation under either nutrient-sufficient or Pi-deficient conditions. Our results demonstrate a key factor controlling the membrane lipid profile during the Pi starvation response in N. oceanica.
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Base de dados:
MEDLINE
Assunto principal:
Fosfatos
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Fatores de Transcrição
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Proteínas de Algas
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Metabolismo dos Lipídeos
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Microalgas
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Lipídeos de Membrana
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article