Structural Features of 1,3,4-Thiadiazole-Derived Ligands and Their Zn(II) and Cu(II) Complexes Which Demonstrate Synergistic Antibacterial Effects with Kanamycin.

Karcz, Dariusz; Matwijczuk, Arkadiusz; Kaminski, Daniel; Creaven, Bernadette; Ciszkowicz, Ewa; Lecka-Szlachta, Katarzyna; Starzak, Karolina

Karcz, Dariusz; Matwijczuk, Arkadiusz; Kaminski, Daniel; Creaven, Bernadette; Ciszkowicz, Ewa; Lecka-Szlachta, Katarzyna; Starzak, Karolina.

Afiliação

Karcz D; Department of Analytical Chemistry (C1), Faculty of Chemical Engineering and Technology, Cracow University of Technology, 31155 Kraków, Poland.
Matwijczuk A; Department of Biophysics, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Kaminski D; Department of General and Coordination Chemistry and Crystallography, Institute of Chemical Sciences, Maria Curie-Sklodowska University in Lublin, 20-031 Lublin, Poland.
Creaven B; School of Chemical and Pharmaceutical Sciences, Technological University Dublin, Kevin St., D2 Dublin, Ireland.
Ciszkowicz E; Department of Biotechnology and Bioinformatics, Faculty of Chemistry, Rzeszow University of Technology, 35-959 Rzeszów, Poland.
Lecka-Szlachta K; Department of Biotechnology and Bioinformatics, Faculty of Chemistry, Rzeszow University of Technology, 35-959 Rzeszów, Poland.
Starzak K; Department of Analytical Chemistry (C1), Faculty of Chemical Engineering and Technology, Cracow University of Technology, 31155 Kraków, Poland.

Int J Mol Sci ; 21(16)2020 Aug 10.

Article em En | MEDLINE | ID: mdl-32785125

Assuntos

Antibacterianos/farmacologia; Antioxidantes/farmacologia; Complexos de Coordenação/farmacologia; Cobre/química; Canamicina/farmacologia; Tiadiazóis/química; Zinco/química; Cromatografia Líquida; Complexos de Coordenação/síntese química; Sinergismo Farmacológico; Ligantes; Espectroscopia de Ressonância Magnética; Espectrometria de Massas; Testes de Sensibilidade Microbiana; Espectroscopia de Infravermelho com Transformada de Fourier; Staphylococcus aureus/efeitos dos fármacos; Difração de Raios X

Palavras-chave

1,3,4-thiadiazole; antibacterial; antioxidant; kanamycin; neurodegeneration; synergistic effect; thiadiazole complex; thiadiazole ligands

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiadiazóis / Zinco / Canamicina / Cobre / Complexos de Coordenação / Antibacterianos / Antioxidantes Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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