Sex matters: XIST and DDX3Y gene expression as a tool to determine fetal sex in human first trimester placenta.
Placenta
; 97: 68-70, 2020 08.
Article
em En
| MEDLINE
| ID: mdl-32792067
ABSTRACT
Fetal sex influences placental function as well as maternal and fetal health, being an important factor to consider in pregnancy studies. However, fetal sex determination in the first trimester of pregnancy still faces some technical limitations. Here we describe an RT-qPCR technique to determine fetal sex based on X-inactive specific transcript (XIST) and DEAD-Box helicase 3 Y-linked (DDX3Y) gene expression. This method is straightforward, reliable, fast and applicable on both, placental tissue and primary cells.
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Base de dados:
MEDLINE
Assunto principal:
Placenta
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Primeiro Trimestre da Gravidez
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Análise para Determinação do Sexo
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Expressão Gênica
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Antígenos de Histocompatibilidade Menor
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RNA Helicases DEAD-box
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RNA Longo não Codificante
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article