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Corneal ulceration associated with dupilumab use in a patient with atopic dermatitis.
Li, Gavin; Berkenstock, Meghan; Soiberman, Uri.
Afiliação
  • Li G; The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 600 North Wolfe St, Baltimore, MD, 21237, USA.
  • Berkenstock M; The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 600 North Wolfe St, Baltimore, MD, 21237, USA.
  • Soiberman U; The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 600 North Wolfe St, Baltimore, MD, 21237, USA.
Am J Ophthalmol Case Rep ; 19: 100848, 2020 Sep.
Article em En | MEDLINE | ID: mdl-32793843
ABSTRACT

PURPOSE:

To describe a case of corneal ulceration associated with dupilumab use for atopic dermatitis. OBSERVATIONS A patient developed an inflammatory corneal ulcer 3 weeks after starting bi-weekly intravenous dupilumab therapy. Symptoms resolved with topical prednisolone and discontinuation of the systemic therapy with dupilumab. CONCLUSION AND IMPORTANCE Dupilumab is known to cause ocular surface inflammation, but we report a novel association between dupilumab use and potentially sight-threatening corneal ulceration.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article