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ß-Cell-Specific Deletion of HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) Reductase Causes Overt Diabetes due to Reduction of ß-Cell Mass and Impaired Insulin Secretion.
Takei, Shoko; Nagashima, Shuichi; Takei, Akihito; Yamamuro, Daisuke; Wakabayashi, Tetsuji; Murakami, Akiko; Isoda, Masayo; Yamazaki, Hisataka; Ebihara, Chihiro; Takahashi, Manabu; Ebihara, Ken; Dezaki, Katsuya; Takayanagi, Yuki; Onaka, Tatsushi; Fujiwara, Ken; Yashiro, Takashi; Ishibashi, Shun.
Afiliação
  • Takei S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Nagashima S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Takei A; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Yamamuro D; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Wakabayashi T; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Murakami A; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Isoda M; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Yamazaki H; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Ebihara C; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Takahashi M; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Ebihara K; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Dezaki K; Division of Integrative Physiology, Department of Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Takayanagi Y; Division of Brain and Neurophysiology, Department of Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Onaka T; Division of Brain and Neurophysiology, Department of Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Fujiwara K; Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Yashiro T; Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.
  • Ishibashi S; Division of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan ishibash@jichi.ac.jp.
Diabetes ; 69(11): 2352-2363, 2020 11.
Article em En | MEDLINE | ID: mdl-32796082
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Enzimológica da Expressão Gênica / Células Secretoras de Insulina / Hidroximetilglutaril-CoA Redutases / Insulina Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Enzimológica da Expressão Gênica / Células Secretoras de Insulina / Hidroximetilglutaril-CoA Redutases / Insulina Idioma: En Ano de publicação: 2020 Tipo de documento: Article