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Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones.
Clarelli, Fabrizio; Palmer, Adam; Singh, Bhupender; Storflor, Merete; Lauksund, Silje; Cohen, Ted; Abel, Sören; Abel Zur Wiesch, Pia.
Afiliação
  • Clarelli F; Department of Pharmacy, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway.
  • Palmer A; Department of Biology, Eberly College of Science, The Pennsylvania State University, University Park, PA, United States of America.
  • Singh B; Center for Infectious Disease Dynamics, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, United States of America.
  • Storflor M; Department of Pharmacology, Computational Medicine Program, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
  • Lauksund S; Department of Pharmacy, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway.
  • Cohen T; Department of Pharmacy, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway.
  • Abel S; Department of Veterinary and Biomedical Sciences, College of Agricultural Sciences, The Pennsylvania State University, PA, United States of America.
  • Abel Zur Wiesch P; Department of Pharmacy, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway.
PLoS Comput Biol ; 16(8): e1008106, 2020 08.
Article em En | MEDLINE | ID: mdl-32797079
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolonas / Biologia Computacional / Desenvolvimento de Medicamentos / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinolonas / Biologia Computacional / Desenvolvimento de Medicamentos / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article