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A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant.
Jones, Alistair; Barker-Haliski, Melissa; Ilie, Andrei S; Herd, Murray B; Baxendale, Sarah; Holdsworth, Celia J; Ashton, John-Paul; Placzek, Marysia; Jayasekera, Bodiabaduge A P; Cowie, Christopher J A; Lambert, Jeremy J; Trevelyan, Andrew J; White, H Steve; Marson, Anthony G; Cunliffe, Vincent T; Sills, Graeme J; Morgan, Alan.
Afiliação
  • Jones A; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Barker-Haliski M; Department of Pharmacy, University of Washington, Seattle.
  • Ilie AS; Institute of Neuroscience, University of Newcastle, Newcastle, UK.
  • Herd MB; Neuroscience, Division of Systems Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
  • Baxendale S; Department of Biomedical Science, University of Sheffield, Sheffield, UK.
  • Holdsworth CJ; Department of Biomedical Science, University of Sheffield, Sheffield, UK.
  • Ashton JP; Department of Biomedical Science, University of Sheffield, Sheffield, UK.
  • Placzek M; Department of Biomedical Science, University of Sheffield, Sheffield, UK.
  • Jayasekera BAP; Institute of Neuroscience, University of Newcastle, Newcastle, UK.
  • Cowie CJA; Department of Neurosurgery, Royal Victoria Infirmary, Newcastle, UK.
  • Lambert JJ; Institute of Neuroscience, University of Newcastle, Newcastle, UK.
  • Trevelyan AJ; Department of Neurosurgery, Royal Victoria Infirmary, Newcastle, UK.
  • White HS; Neuroscience, Division of Systems Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
  • Marson AG; Institute of Neuroscience, University of Newcastle, Newcastle, UK.
  • Cunliffe VT; Department of Pharmacy, University of Washington, Seattle.
  • Sills GJ; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Morgan A; Department of Biomedical Science, University of Sheffield, Sheffield, UK.
Epilepsia ; 61(10): 2106-2118, 2020 10.
Article em En | MEDLINE | ID: mdl-32797628
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Receptores de GABA-A / Descoberta de Drogas / Agonistas de Receptores de GABA-A / Anticonvulsivantes Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Receptores de GABA-A / Descoberta de Drogas / Agonistas de Receptores de GABA-A / Anticonvulsivantes Idioma: En Ano de publicação: 2020 Tipo de documento: Article