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IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
Ahmad, Amais; Pepin, Xavier; Aarons, Leon; Wang, Yuya; Darwich, Adam S; Wood, J Matthew; Tannergren, Christer; Karlsson, Eva; Patterson, Claire; Thörn, Helena; Ruston, Linette; Mattinson, Alex; Carlert, Sara; Berg, Staffan; Murphy, Donal; Engman, Helena; Laru, Johanna; Barker, Richard; Flanagan, Talia; Abrahamsson, Bertil; Budhdeo, Shanoo; Franek, Frans; Moir, Andrea; Hanisch, Gunilla; Pathak, Shriram M; Turner, David; Jamei, Masoud; Brown, Jonathan; Good, David; Vaidhyanathan, Shruthi; Jackson, Claire; Nicolas, Olivier; Beilles, Stephane; Nguefack, Jean-Flaubert; Louit, Guillaume; Henrion, Louis; Ollier, Celine; Boulu, Laurent; Xu, Christine; Heimbach, Tycho; Ren, Xiojun; Lin, Wen; Nguyen-Trung, Anh-Thu; Zhang, Jin; He, Handan; Wu, Fan; Bolger, Michael B; Mullin, James M; van Osdol, Bill; Szeto, Ke.
Afiliação
  • Ahmad A; University of Manchester, United Kingdom. Electronic address: amais.ahmed@manchester.ac.uk.
  • Pepin X; AstraZeneca, United Kingdom.
  • Aarons L; University of Manchester, United Kingdom.
  • Wang Y; University of Manchester, United Kingdom.
  • Darwich AS; Royal Institute of Technology, Stockholm, Sweden.
  • Wood JM; AstraZeneca, United Kingdom.
  • Tannergren C; AstraZeneca, United Kingdom.
  • Karlsson E; AstraZeneca, United Kingdom.
  • Patterson C; AstraZeneca, United Kingdom.
  • Thörn H; AstraZeneca, United Kingdom.
  • Ruston L; AstraZeneca, United Kingdom.
  • Mattinson A; AstraZeneca, United Kingdom.
  • Carlert S; AstraZeneca, United Kingdom.
  • Berg S; AstraZeneca, United Kingdom.
  • Murphy D; AstraZeneca, United Kingdom.
  • Engman H; AstraZeneca, United Kingdom.
  • Laru J; AstraZeneca, United Kingdom.
  • Barker R; AstraZeneca, United Kingdom.
  • Flanagan T; AstraZeneca, United Kingdom.
  • Abrahamsson B; AstraZeneca, United Kingdom.
  • Budhdeo S; AstraZeneca, United Kingdom.
  • Franek F; AstraZeneca, United Kingdom.
  • Moir A; AstraZeneca, United Kingdom.
  • Hanisch G; AstraZeneca, United Kingdom.
  • Pathak SM; Certara, Simcyp Division, United Kingdom.
  • Turner D; Certara, Simcyp Division, United Kingdom.
  • Jamei M; Certara, Simcyp Division, United Kingdom.
  • Brown J; Bristol-Myers Squibb, United Kingdom.
  • Good D; Bristol-Myers Squibb, United Kingdom.
  • Vaidhyanathan S; Bristol-Myers Squibb, United Kingdom.
  • Jackson C; Bristol-Myers Squibb, United Kingdom.
  • Nicolas O; Sanofi, United States.
  • Beilles S; Sanofi, United States.
  • Nguefack JF; Sanofi, United States.
  • Louit G; Sanofi, United States.
  • Henrion L; Sanofi, United States.
  • Ollier C; Sanofi, United States.
  • Boulu L; Sanofi, United States.
  • Xu C; Sanofi, United States.
  • Heimbach T; Novartis, United States.
  • Ren X; Novartis, United States.
  • Lin W; Novartis, United States.
  • Nguyen-Trung AT; Novartis, United States.
  • Zhang J; Novartis, United States.
  • He H; Novartis, United States.
  • Wu F; Novartis, United States.
  • Bolger MB; Simulation Plus, Inc., United States.
  • Mullin JM; Simulation Plus, Inc., United States.
  • van Osdol B; Simulation Plus, Inc., United States.
  • Szeto K; Simulation Plus, Inc., United States.
Eur J Pharm Biopharm ; 156: 50-63, 2020 Nov.
Article em En | MEDLINE | ID: mdl-32805361
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biofarmácia / Software / Preparações Farmacêuticas / Análise de Dados / Absorção Intestinal / Modelos Biológicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biofarmácia / Software / Preparações Farmacêuticas / Análise de Dados / Absorção Intestinal / Modelos Biológicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article