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3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.
Badder, Luned M; Hollins, Andrew J; Herpers, Bram; Yan, Kuan; Ewan, Kenneth B; Thomas, Mairian; Shone, Jennifer R; Badder, Delyth A; Naven, Marc; Ashelford, Kevin E; Hargest, Rachel; Clarke, Alan R; Esdar, Christina; Buchstaller, Hans-Peter; Treherne, J Mark; Boj, Sylvia; Ramezanpour, Bahar; Wienke, Dirk; Price, Leo S; Shaw, Paul H; Dale, Trevor C.
Afiliação
  • Badder LM; Cardiff University School of Biosciences, Cardiff, Wales, United Kingdom.
  • Hollins AJ; European Cancer Stem Cell Research Institute (ECSCRI), Cardiff University, Cardiff, Wales, United Kingdom.
  • Herpers B; Cardiff University School of Biosciences, Cardiff, Wales, United Kingdom.
  • Yan K; European Cancer Stem Cell Research Institute (ECSCRI), Cardiff University, Cardiff, Wales, United Kingdom.
  • Ewan KB; OcellO B.V., Leiden, The Netherlands.
  • Thomas M; OcellO B.V., Leiden, The Netherlands.
  • Shone JR; Cardiff University School of Biosciences, Cardiff, Wales, United Kingdom.
  • Badder DA; Cellesce Ltd, Cardiff Medicentre, Heath Park, Cardiff, United Kingdom.
  • Naven M; Cardiff University School of Biosciences, Cardiff, Wales, United Kingdom.
  • Ashelford KE; Cellular Pathology Department, University Hospital for Wales, Cardiff, United Kingdom.
  • Hargest R; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom.
  • Clarke AR; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, United Kingdom.
  • Esdar C; Department of Colorectal Surgery, University Hospital of Wales, Cardiff, United Kingdom.
  • Buchstaller HP; Division of Cancer and Genetics, CCMRC, Henry Wellcome Building, Cardiff University, Cardiff, United Kingdom.
  • Treherne JM; European Cancer Stem Cell Research Institute (ECSCRI), Cardiff University, Cardiff, Wales, United Kingdom.
  • Boj S; Biopharma, Merck Healthcare KGaA, Research & Development, Darmstadt, Germany.
  • Ramezanpour B; Biopharma, Merck Healthcare KGaA, Research & Development, Darmstadt, Germany.
  • Wienke D; Cellesce Ltd, Cardiff Medicentre, Heath Park, Cardiff, United Kingdom.
  • Price LS; Hubrecht Organoid Technology, Utrecht, The Netherlands.
  • Shaw PH; Hubrecht Organoid Technology, Utrecht, The Netherlands.
  • Dale TC; Biopharma, Merck Healthcare KGaA, Research & Development, Darmstadt, Germany.
PLoS One ; 15(8): e0235319, 2020.
Article em En | MEDLINE | ID: mdl-32810173
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Organoides / Tanquirases / Inibidores Enzimáticos / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Organoides / Tanquirases / Inibidores Enzimáticos / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article