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A Rare Presentation of Concurrent Onset and Coexistence of Generalized Lichen Planus and Psoriasis in a Child.
Sandhu, Sunmeet; Sinha, Preema; Shelly, Divya; Bhatt, Siddharth.
Afiliação
  • Sandhu S; Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.
  • Sinha P; Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.
  • Shelly D; Department of Pathology, Armed Forces Medical College, Pune, Maharashtra, India.
  • Bhatt S; Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.
Indian Dermatol Online J ; 11(4): 616-618, 2020.
Article em En | MEDLINE | ID: mdl-32832455
ABSTRACT
Independently, psoriasis and lichen planus (LP) are common inflammatory skin conditions affecting around 2-3% and 1% of the population, respectively. However, the coexistence of both diseases is rare. Common immunological mechanisms with altered T-cell-mediated autoimmunity, cytokine milieu, and Koebner phenomenon play a role in their pathogenesis. As reviewed in the literature, psoriasis may independently be associated with other autoimmune conditions like vitiligo, alopecia areata, LP, and discoid lupus erythematosus. A rare co-occurrence of these two or three autoimmune diseases has been reported. Here, we report a case of a 10-year-old boy who presented with persistent nonpruritic multiple hyperpigmented scaly papules and plaques over the body since 6 months of age. Histopathology revealed features suggestive of both LP and psoriasis in the same section. A diagnosis of psoriasis-LP overlap was made, and the patient was managed with tab acitretin 25 mg daily and narrowband ultraviolet B (NBUVB) phototherapy with which he showed satisfactory clearance of the lesions.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article