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Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway.
Xiao, Xiansha; Elsayed, Somayah S; Wu, Changsheng; van der Heul, Helga U; Metsä-Ketelä, Mikko; Du, Chao; Prota, Andrea E; Chen, Chun-Chi; Liu, Weidong; Guo, Rey-Ting; Abrahams, Jan Pieter; van Wezel, Gilles P.
Afiliação
  • Xiao X; Molecular Biotechnology, Leiden University, PO Box 9505, 2300RA Leiden, The Netherlands.
  • Elsayed SS; Molecular Biotechnology, Leiden University, PO Box 9505, 2300RA Leiden, The Netherlands.
  • Wu C; State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, Shandong 266237, P. R. China.
  • van der Heul HU; Molecular Biotechnology, Leiden University, PO Box 9505, 2300RA Leiden, The Netherlands.
  • Metsä-Ketelä M; Department of Biochemistry and Food Chemistry, University of Turku, FIN-20014 Turku, Finland.
  • Du C; Molecular Biotechnology, Leiden University, PO Box 9505, 2300RA Leiden, The Netherlands.
  • Prota AE; Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institut, CH-5232 Villigen, Switzerland.
  • Chen CC; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei 43420, P. R. China.
  • Liu W; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei 43420, P. R. China.
  • Guo RT; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei 43420, P. R. China.
  • Abrahams JP; Molecular Biotechnology, Leiden University, PO Box 9505, 2300RA Leiden, The Netherlands.
  • van Wezel GP; Bio-nano diffraction Biozentrum, Paul Scherrer Institut, CH-5232 Villigen, Switzerland.
ACS Chem Biol ; 15(9): 2529-2538, 2020 09 18.
Article em En | MEDLINE | ID: mdl-32840360
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredutases do Álcool / Policetídeos / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxirredutases do Álcool / Policetídeos / Antibacterianos Idioma: En Ano de publicação: 2020 Tipo de documento: Article