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Development of Novel AKR1C3 Inhibitors as New Potential Treatment for Castration-Resistant Prostate Cancer.
Endo, Satoshi; Oguri, Hiroaki; Segawa, Jin; Kawai, Mina; Hu, Dawei; Xia, Shuang; Okada, Takuya; Irie, Katsumasa; Fujii, Shinya; Gouda, Hiroaki; Iguchi, Kazuhiro; Matsukawa, Takuo; Fujimoto, Naohiro; Nakayama, Toshiyuki; Toyooka, Naoki; Matsunaga, Toshiyuki; Ikari, Akira.
Afiliação
  • Endo S; Laboratory of Biochemistry, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
  • Oguri H; Laboratory of Biochemistry, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
  • Segawa J; Laboratory of Biochemistry, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
  • Kawai M; Laboratory of Biochemistry, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
  • Hu D; Graduate School of Innovative Life Science, University of Toyama, Toyama 930-8555, Japan.
  • Xia S; Graduate School of Innovative Life Science, University of Toyama, Toyama 930-8555, Japan.
  • Okada T; Graduate School of Innovative Life Science, University of Toyama, Toyama 930-8555, Japan.
  • Irie K; Cellular and Structural Physiology Institute, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8601, Japan.
  • Fujii S; Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8601, Japan.
  • Gouda H; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.
  • Iguchi K; School of Pharmacy, Showa University, Tokyo 142-8555, Japan.
  • Matsukawa T; Laboratory of Community Pharmacy, Department of Pharmacy, Gifu Pharmaceutical University, Gifu 501-1196, Japan.
  • Fujimoto N; Department of Urology, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan.
  • Nakayama T; Department of Urology, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan.
  • Toyooka N; Department of Pathology, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan.
  • Matsunaga T; Graduate School of Innovative Life Science, University of Toyama, Toyama 930-8555, Japan.
  • Ikari A; Education Center of Green Pharmaceutical Sciences, Gifu Pharmaceutical University, Gifu 502-8585, Japan.
J Med Chem ; 63(18): 10396-10411, 2020 09 24.
Article em En | MEDLINE | ID: mdl-32847363
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Neoplasias de Próstata Resistentes à Castração / Membro C3 da Família 1 de alfa-Ceto Redutase / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Neoplasias de Próstata Resistentes à Castração / Membro C3 da Família 1 de alfa-Ceto Redutase / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article