Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages.

Subramani, Aarthi; Griggs, Prianca; Frantzen, Niah; Mendez, James; Tucker, Jamila; Murriel, Jada; Sircy, Linda M; Millican, Grace E; McClelland, Erin E; Seipelt-Thiemann, Rebecca L; Nelson, David E

Subramani, Aarthi; Griggs, Prianca; Frantzen, Niah; Mendez, James; Tucker, Jamila; Murriel, Jada; Sircy, Linda M; Millican, Grace E; McClelland, Erin E; Seipelt-Thiemann, Rebecca L; Nelson, David E.

Afiliação

Subramani A; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.
Griggs P; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.
Frantzen N; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.
Mendez J; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.
Tucker J; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.
Murriel J; Microbiology, Immunology, and Molecular Genetics Department, University of Kentucky, Lexington, KY, United States of America.
Sircy LM; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.
Millican GE; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.
McClelland EE; Department of Pathology, University of Utah, Salt Lake City, UT, United States of America.
Seipelt-Thiemann RL; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.
Nelson DE; Biology Department, Middle Tennessee State University, Murfreesboro, TN, United States of America.

PLoS One ; 15(8): e0233818, 2020.

Article em En | MEDLINE | ID: mdl-32857777

Assuntos

Cryptococcus neoformans/patogenicidade; Macrófagos/metabolismo; Macrófagos/microbiologia; Animais; Proteínas Reguladoras de Apoptose/genética; Proteínas Reguladoras de Apoptose/metabolismo; Cryptococcus neoformans/imunologia; Ontologia Genética; Redes Reguladoras de Genes; Imunidade Inata/genética; Ativação de Macrófagos/genética; Ativação de Macrófagos/imunologia; Macrófagos/imunologia; Camundongos; Óxido Nítrico Sintase Tipo II/metabolismo; Células RAW 264.7; Transativadores/genética; Transativadores/metabolismo; Transcriptoma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cryptococcus neoformans / Macrófagos Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cryptococcus neoformans / Macrófagos Idioma: En Ano de publicação: 2020 Tipo de documento: Article