Perioperative Outcomes and 5-year Survival After Open versus Thoracoscopic Sleeve Resection for Lung Cancer.
Semin Thorac Cardiovasc Surg
; 33(2): 522-530, 2021.
Article
em En
| MEDLINE
| ID: mdl-32858216
ABSTRACT
The objective of this study was to evaluate the impact of a video-assisted thoracoscopic (VATS) approach on outcomes in patients who underwent sleeve lobectomy for non-small-cell lung cancer (NSCLC). Outcomes of patients with cT1-T3, N0-N2, M0 NSCLC who underwent sleeve lobectomy in the National Cancer Data Base (NCDB) from 2010-2015 were assessed using Kaplan-Meier, propensity score-matching, and Cox proportional hazards analyses. An "intent-to-treat" analysis was performed. In the NCDB, 210 sleeve lobectomy patients met inclusion criteria (VATS 44 [21%], thoracotomy 166 [79%]). Nine (20%) of the VATS cases were converted to open. Compared to an open approach, VATS was associated with no significant differences in lymph nodes examined (median 9.5 vs 9.0; pâ¯=â¯0.72), length of stay (median 6 days vs 6 days; pâ¯=â¯0.36), 30-day mortality (4.5% vs 1.8%; pâ¯=â¯0.28), and 90-day mortality (6.8% vs 4.8%; pâ¯=â¯0.70). There were no significant differences in 5-year survival between the VATS and open groups in both the entire cohort (VATS [85%] vs open [79%]; log-rank pâ¯=â¯0.91) and in a propensity score-matched analysis of 86 patients (log-rank pâ¯=â¯0.75). Furthermore, a VATS approach was also not associated with worse survival in multivariable analysis (HRâ¯=â¯0.64; 95% CI [0.23-1.78]; pâ¯=â¯0.39). In this national analysis, a VATS approach for sleeve lobectomy for NSCLC was not associated with worse short-term or long-term outcomes when compared to an open approach.
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Assunto principal:
Carcinoma Pulmonar de Células não Pequenas
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Neoplasias Pulmonares
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En
Ano de publicação:
2021
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Article