Solid-state NMR spectroscopy identifies three classes of lipids in <i>Cryptococcus neoformans</i> melanized cell walls and whole fungal cells.

Chrissian, Christine; Camacho, Emma; Kelly, John E; Wang, Hsin; Casadevall, Arturo; Stark, Ruth E

Solid-state NMR spectroscopy identifies three classes of lipids in Cryptococcus neoformans melanized cell walls and whole fungal cells.

Chrissian, Christine; Camacho, Emma; Kelly, John E; Wang, Hsin; Casadevall, Arturo; Stark, Ruth E.

Afiliação

Chrissian C; Department of Chemistry and Biochemistry and CUNY Institute for Macromolecular Assemblies, City College of New York, New York, New York, USA; Ph.D. Program in Biochemistry, Graduate Center of the City University of New York, New York, New York, USA.
Camacho E; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Kelly JE; Department of Chemistry and Biochemistry and CUNY Institute for Macromolecular Assemblies, City College of New York, New York, New York, USA.
Wang H; Department of Chemistry and Biochemistry and CUNY Institute for Macromolecular Assemblies, City College of New York, New York, New York, USA.
Casadevall A; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Stark RE; Department of Chemistry and Biochemistry and CUNY Institute for Macromolecular Assemblies, City College of New York, New York, New York, USA; Ph.D. Program in Biochemistry, Graduate Center of the City University of New York, New York, New York, USA; Ph.D. Program in Chemistry, Graduate Center of the

J Biol Chem ; 295(44): 15083-15096, 2020 10 30.

Article em En | MEDLINE | ID: mdl-32859751

Assuntos

Espectroscopia de Ressonância Magnética Nuclear de Carbono-13/métodos; Parede Celular/metabolismo; Cryptococcus neoformans/metabolismo; Lipídeos/classificação; Melaninas/metabolismo; Espectroscopia de Prótons por Ressonância Magnética/métodos; Cryptococcus neoformans/patogenicidade; Lipídeos/análise; Virulência

Palavras-chave

Cryptococcus neoformans; cell wall; fungi; isoprenoid; lipid; lipid droplet; melanin; molecular structure; nuclear magnetic resonance (NMR); solid-state NMR; sterol; triglyceride

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Parede Celular / Cryptococcus neoformans / Espectroscopia de Ressonância Magnética Nuclear de Carbono-13 / Espectroscopia de Prótons por Ressonância Magnética / Lipídeos / Melaninas Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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