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Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Bochel, Alice J; Williams, Christopher; McCoy, Airlie J; Hoppe, Hans-Jürgen; Winter, Ashley J; Nicholls, Ryan D; Harlos, Karl; Jones, E Yvonne; Berger, Imre; Hassan, A Bassim; Crump, Matthew P.
Afiliação
  • Bochel AJ; School of Chemistry, Cantock's Close, University of Bristol, Bristol BS8 1TS, UK.
  • Williams C; School of Chemistry, Cantock's Close, University of Bristol, Bristol BS8 1TS, UK; BrisSynBio, Life Sciences Building, Tyndall Avenue, Bristol BS8 1TQ, UK.
  • McCoy AJ; Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, The Keith Peters Building, Hills Road, Cambridge CB2 0XY, UK.
  • Hoppe HJ; Tumour Growth Control Group, Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK; dAInomics Ltd, 66 High Street, Bassingbourn Royston SG8 5LF, UK.
  • Winter AJ; School of Chemistry, Cantock's Close, University of Bristol, Bristol BS8 1TS, UK.
  • Nicholls RD; School of Chemistry, Cantock's Close, University of Bristol, Bristol BS8 1TS, UK.
  • Harlos K; Cancer Research UK Receptor Structure Research Group, Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Jones EY; Cancer Research UK Receptor Structure Research Group, Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Berger I; School of Biochemistry, University of Bristol, University Walk, Bristol BS8 1TD, UK.
  • Hassan AB; Tumour Growth Control Group, Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK. Electronic address: bass.hassan@path.ox.ac.uk.
  • Crump MP; School of Chemistry, Cantock's Close, University of Bristol, Bristol BS8 1TS, UK; BrisSynBio, Life Sciences Building, Tyndall Avenue, Bristol BS8 1TQ, UK. Electronic address: matt.crump@bristol.ac.uk.
Structure ; 28(12): 1300-1312.e5, 2020 12 01.
Article em En | MEDLINE | ID: mdl-32877646

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor IGF Tipo 2 Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor IGF Tipo 2 Idioma: En Ano de publicação: 2020 Tipo de documento: Article