A controlled, randomized phase II clinical trial for efficacy and safety evaluation of mannuronic acid in secondary progressive form of multiple sclerosis.

Najafi, Soheil; Moghadam, Nahid Beladi; Saadat, Payam; Noorbakhsh, Seyyedeh Masoomeh; Mohammadi, Anita Vali; Manouchehrinia, Ali; Hosseini, Mostafa; Matsuo, Hidenori; Mirshafiey, Abbas

Najafi, Soheil; Moghadam, Nahid Beladi; Saadat, Payam; Noorbakhsh, Seyyedeh Masoomeh; Mohammadi, Anita Vali; Manouchehrinia, Ali; Hosseini, Mostafa; Matsuo, Hidenori; Mirshafiey, Abbas.

Afiliação

Najafi S; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Moghadam NB; Department of Neurology, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.
Saadat P; Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Noorbakhsh SM; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mohammadi AV; Shiraz Branch, Islamic Azad University, Shiraz, Iran.
Manouchehrinia A; Department of Clinical Neuroscience (CNS), Karolinska Institutet, Stockholm, Sweden.
Hosseini M; Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Matsuo H; National Hospital Organization, Nagasaki Kawatana Medical Center, Nagasaki, Japan.
Mirshafiey A; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Int J Neurosci ; 132(4): 403-412, 2022 Apr.

Article em En | MEDLINE | ID: mdl-32878514

Assuntos

Ácidos Hexurônicos; Esclerose Múltipla Crônica Progressiva; Esclerose Múltipla; Adulto; Ácidos Hexurônicos/uso terapêutico; Humanos; Interferon beta-1a/uso terapêutico; Interferon beta-1b/uso terapêutico; Pessoa de Meia-Idade; Esclerose Múltipla/tratamento farmacológico; Esclerose Múltipla Crônica Progressiva/tratamento farmacológico; Adulto Jovem

Palavras-chave

M2000; Mannuronic acid; SPMS; clinical trial; multiple sclerosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esclerose Múltipla Crônica Progressiva / Ácidos Hexurônicos / Esclerose Múltipla Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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