High-intensity interval training reduces neutrophil-to-lymphocyte ratio in persons with multiple sclerosis during inpatient rehabilitation.
Mult Scler
; 27(7): 1136-1139, 2021 06.
Article
em En
| MEDLINE
| ID: mdl-32880214
In persons with multiple sclerosis (PwMS), the neutrophil-to-lymphocyte ratio (NLR) is associated with disability status, symptomatology and disease activity. High-intensity interval training (HIIT) improves many symptoms in PwMS and may positively influence disease progression. Here, we present results from a randomized controlled trial during inpatient rehabilitation on immediate (single bout) and training (3-week intervention) effects of HIIT versus moderate continuous training on NLR and related cellular inflammation markers. Only HIIT reduced the NLR over the 3-week intervention period. These training effects might be due to repetitive inflammatory states with compensatory anti-inflammatory counterbalancing after each HIIT session.
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MEDLINE
Assunto principal:
Treinamento Intervalado de Alta Intensidade
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Esclerose Múltipla
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article