Dynamics of Islet Autoantibodies During Prospective Follow-Up From Birth to Age 15 Years.

Pöllänen, Petra M; Ryhänen, Samppa J; Toppari, Jorma; Ilonen, Jorma; Vähäsalo, Paula; Veijola, Riitta; Siljander, Heli; Knip, Mikael

Pöllänen, Petra M; Ryhänen, Samppa J; Toppari, Jorma; Ilonen, Jorma; Vähäsalo, Paula; Veijola, Riitta; Siljander, Heli; Knip, Mikael.

Afiliação

Pöllänen PM; Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Ryhänen SJ; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Toppari J; Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Ilonen J; Department of Pediatrics, Turku University Hospital, and Institute of Biomedicine and Centre for Population Health Research, University of Turku, Turku, Finland.
Vähäsalo P; Immunogenetics Laboratory, Institute of Biomedicine, University of Turku and Clinical Microbiology, Turku University Hospital, Turku, Finland.
Veijola R; Department of Pediatrics, PEDEGO Research Group, Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.
Siljander H; Department of Pediatrics, PEDEGO Research Group, Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.
Knip M; Pediatric Research Center, Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

J Clin Endocrinol Metab ; 105(12)2020 12 01.

Article em En | MEDLINE | ID: mdl-32882033

Assuntos

Autoanticorpos/sangue; Autoimunidade/genética; Diabetes Mellitus Tipo 1/genética; Ilhotas Pancreáticas/imunologia; Adolescente; Autoanticorpos/análise; Criança; Desenvolvimento Infantil/fisiologia; Pré-Escolar; Diabetes Mellitus Tipo 1/diagnóstico; Diabetes Mellitus Tipo 1/epidemiologia; Diabetes Mellitus Tipo 1/imunologia; Feminino; Finlândia/epidemiologia; Seguimentos; Predisposição Genética para Doença; Glutamato Descarboxilase/imunologia; Antígenos HLA/genética; Humanos; Lactente; Recém-Nascido; Anticorpos Anti-Insulina/análise; Anticorpos Anti-Insulina/sangue; Masculino; Prognóstico; Estudos Prospectivos; Proteínas Tirosina Fosfatases Classe 8 Semelhantes a Receptores/imunologia; Fatores de Tempo; Transportador 8 de Zinco/genética; Transportador 8 de Zinco/imunologia

Palavras-chave

HLA; children; dynamics; islet autoantibodies; prediction; type 1 diabetes

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoanticorpos / Autoimunidade / Ilhotas Pancreáticas / Diabetes Mellitus Tipo 1 Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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