Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes.

Li, Hao-Jv; Wei, Wen-Long; Li, Zhen-Wei; Yao, Chang-Liang; Wang, Meng-Yuan; Zhang, Jian-Qing; Li, Jia-Yuan; Guo, De-An

Li, Hao-Jv; Wei, Wen-Long; Li, Zhen-Wei; Yao, Chang-Liang; Wang, Meng-Yuan; Zhang, Jian-Qing; Li, Jia-Yuan; Guo, De-An.

Afiliação

Li HJ; Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road 501, Shanghai, 201203, China.
Wei WL; University of Chinese Academy of Sciences, Beijing, 100049, China.
Li ZW; Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road 501, Shanghai, 201203, China.
Yao CL; Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road 501, Shanghai, 201203, China.
Wang MY; University of Chinese Academy of Sciences, Beijing, 100049, China.
Zhang JQ; Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road 501, Shanghai, 201203, China.
Li JY; Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Haike Road 501, Shanghai, 201203, China.
Guo DA; University of Chinese Academy of Sciences, Beijing, 100049, China.

Anal Bioanal Chem ; 412(28): 7891-7897, 2020 Nov.

Article em En | MEDLINE | ID: mdl-32888045

Assuntos

Microssomos Hepáticos/metabolismo; Uncaria/metabolismo; Animais; Cromatografia Líquida de Alta Pressão/métodos; Cães; Haplorrinos; Humanos; Camundongos; Ratos; Especificidade da Espécie; Espectrometria de Massas por Ionização por Electrospray/métodos; Suínos; Espectrometria de Massas em Tandem/métodos

Palavras-chave

Indole alkaloids; Liver microsomes; Mass defect filter; Metabolite identification; Time-staggered targeted ion lists; Uncaria rhynchophylla

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Microssomos Hepáticos / Uncaria Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Microssomos Hepáticos / Uncaria Idioma: En Ano de publicação: 2020 Tipo de documento: Article