Whipple's disease orbitopathy: case report and review of literature.
Orbit
; 41(1): 112-117, 2022 Feb.
Article
em En
| MEDLINE
| ID: mdl-32912014
ABSTRACT
A 59-year-old female patient was diagnosed with Whipple's disease (WD) after several months of constitutional complaints and adenopathies that were initially misinterpreted as sarcoidosis. Initial treatment included doxycycline, hydroxychloroquine and prednisolone, which was suspended due to long-term clinical stability. Four months after prednisolone suspension, the patient presented with right periorbital oedema and erythema. Ophthalmological examination revealed restricted eye movements. A computed tomography (CT) scan demonstrated signs of myositis. The patient was treated with anti-inflammatory and antibiotic drugs, that induced remission of the orbitopathy. During the following two years, she presented three relapses, affecting both the right or the left eyes. The last episode was also associated with systemic corticosteroid tapering. Orbitopathy is a rare form of WD presentation and the diagnosis of this condition may be challenging. As the clinical spectrum may range from an incidentaloma to a severe compressive neuropathy, proper recognition and management of WD orbitopathy is essential.
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Base de dados:
MEDLINE
Assunto principal:
Oftalmopatia de Graves
/
Doença de Whipple
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article