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Design, synthesis and evaluation of novel indirubin-based N-hydroxybenzamides, N-hydroxypropenamides and N-hydroxyheptanamides as histone deacetylase inhibitors and antitumor agents.
Anh, Duong Tien; Hai, Pham-The; Dung, Do Thi Mai; Dung, Phan Thi Phuong; Huong, Le-Thi-Thu; Park, Eun Jae; Jun, Hye Won; Kang, Jong Soon; Kwon, Joo-Hee; Tung, Truong Thanh; Han, Sang-Bae; Nam, Nguyen-Hai.
Afiliação
  • Anh DT; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam.
  • Hai PT; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam.
  • Dung DTM; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam.
  • Dung PTP; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam.
  • Huong LT; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam.
  • Park EJ; College of Pharmacy, Chungbuk National University, 194-31, Osongsaengmyung-1, Heungdeok, Cheongju, Chungbuk 28160, Republic of Korea.
  • Jun HW; College of Pharmacy, Chungbuk National University, 194-31, Osongsaengmyung-1, Heungdeok, Cheongju, Chungbuk 28160, Republic of Korea.
  • Kang JS; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Chungbuk, Republic of Korea.
  • Kwon JH; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Chungbuk, Republic of Korea.
  • Tung TT; Faculty of Pharmacy, PHENIKAA University, Hanoi 12116, Viet Nam; PHENIKAA Institute for Advanced Study (PIAS), PHENIKAA University, Hanoi 12116, Viet Nam.
  • Han SB; College of Pharmacy, Chungbuk National University, 194-31, Osongsaengmyung-1, Heungdeok, Cheongju, Chungbuk 28160, Republic of Korea. Electronic address: shan@chungbuk.ac.kr.
  • Nam NH; Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Hanoi, Viet Nam. Electronic address: namnh@hup.edu.vn.
Bioorg Med Chem Lett ; 30(22): 127537, 2020 11 15.
Article em En | MEDLINE | ID: mdl-32916298
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histona Desacetilase 2 / Inibidores de Histona Desacetilases / Desacetilase 6 de Histona / Amidas / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histona Desacetilase 2 / Inibidores de Histona Desacetilases / Desacetilase 6 de Histona / Amidas / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article