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An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance.
Junco, Jacob J; Chen, Taylor; Rashid, Raushan; Terrell, Maci; Gant, Vincent U; Miller, Matthew; Rau, Rachel; Lacorazza, H Daniel; Rabin, Karen R.
Afiliação
  • Junco JJ; Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA. junco@bcm.edu.
  • Chen T; Department of Pathology & Immunology, BCM, Houston, TX, USA.
  • Rashid R; Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
  • Terrell M; Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
  • Gant VU; Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
  • Miller M; Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
  • Rau R; Stem Cells and Regenerative Medicine Center, Departments of Pediatrics and of Molecular & Human Genetics, BCM, Houston, TX, USA.
  • Lacorazza HD; Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine (BCM), Houston, TX, USA.
  • Rabin KR; Stem Cells and Regenerative Medicine Center, Departments of Pediatrics and of Molecular & Human Genetics, BCM, Houston, TX, USA.
Leukemia ; 35(6): 1777-1781, 2021 06.
Article em En | MEDLINE | ID: mdl-32918044

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Proto-Oncogênicas p21(ras) / Integrases / Penetrância / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Mutação Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Proto-Oncogênicas p21(ras) / Integrases / Penetrância / Leucemia-Linfoma Linfoblástico de Células T Precursoras / Mutação Idioma: En Ano de publicação: 2021 Tipo de documento: Article