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Acquisition of chromosome 1q duplication in parental and genome-edited human-induced pluripotent stem cell-derived neural stem cells results in their higher proliferation rate in vitro and in vivo.
Mehrjardi, Narges Zare; Molcanyi, Marek; Hatay, Firuze Fulya; Timmer, Marco; Shahbazi, Ebrahim; Ackermann, Justus P; Herms, Stefan; Heilmann-Heimbach, Stefanie; Wunderlich, Thomas F; Prochnow, Nora; Haghikia, Aiden; Lampert, Angelika; Hescheler, Jürgen; Neugebauer, Edmund A M; Baharvand, Hossein; Saric, Tomo.
Afiliação
  • Mehrjardi NZ; Center for Physiology and Pathophysiology, Institute for Neurophysiology, Medical Faculty, University of Cologne, Cologne, Germany.
  • Molcanyi M; Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
  • Hatay FF; Center for Physiology and Pathophysiology, Institute for Neurophysiology, Medical Faculty, University of Cologne, Cologne, Germany.
  • Timmer M; Center for Physiology and Pathophysiology, Institute for Neurophysiology, Medical Faculty, University of Cologne, Cologne, Germany.
  • Shahbazi E; Department of Neurosurgery, University Hospital Cologne, Cologne, Germany.
  • Ackermann JP; Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
  • Herms S; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
  • Heilmann-Heimbach S; Department of Genomics, Life & Brain Center, Institute for Human Genetics, University of Bonn, Bonn, Germany.
  • Wunderlich TF; Department of Biomedicine, Medical Genetics, Research Group Genomics, University Hospital Basel, Basel, Switzerland.
  • Prochnow N; Department of Genomics, Life & Brain Center, Institute for Human Genetics, University of Bonn, Bonn, Germany.
  • Haghikia A; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
  • Lampert A; Max Planck Institute for Metabolism Research and Institute for Genetics, University of Cologne, Cologne, Germany.
  • Hescheler J; Cologne Cluster of Excellence in Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.
  • Neugebauer EAM; Clinic for Neurology, St. Josef-Hospital, Clinic of the Ruhr-University Bochum, Bochum, Germany.
  • Baharvand H; Clinic for Neurology, St. Josef-Hospital, Clinic of the Ruhr-University Bochum, Bochum, Germany.
  • Saric T; Institute of Physiology, Uniklinik, RWTH Aachen University, Aachen, Germany.
Cell Prolif ; 53(10): e12892, 2020 Oct.
Article em En | MEDLINE | ID: mdl-32918782
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 1 / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais / Edição de Genes Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 1 / Células-Tronco Pluripotentes Induzidas / Células-Tronco Neurais / Edição de Genes Idioma: En Ano de publicação: 2020 Tipo de documento: Article