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Rhopaladins' analogue (E)-2-aroyl-4-(4-fluorobenzylidene)-5-oxopyrrolidines inhibit proliferation, promote apoptosis and down-regulation of E6/E7 mRNA in cervical cancer.
Zhu, Xiu-Lian; Tian, Xiao-Qiong; Xu, Huan-Huan; Wang, Hong-Mei; Chen, Qin-Hua; Zeng, Xiao-Hua.
Afiliação
  • Zhu XL; Affiliated Dongfeng Hospital, Hubei University of Medicine, Shiyan 442000, PR China; Shenzhen Baoan Authentic TCM Therapy Hospital, Shenzhen, Guangdong 518101, PR China; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmaceutical Sciences, Hubei University of Medicine, H
  • Tian XQ; Affiliated Dongfeng Hospital, Hubei University of Medicine, Shiyan 442000, PR China; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmaceutical Sciences, Hubei University of Medicine, Hubei 442000, PR China.
  • Xu HH; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmaceutical Sciences, Hubei University of Medicine, Hubei 442000, PR China.
  • Wang HM; Affiliated Dongfeng Hospital, Hubei University of Medicine, Shiyan 442000, PR China; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmaceutical Sciences, Hubei University of Medicine, Hubei 442000, PR China. Electronic address: meirwang@126.com.
  • Chen QH; Shenzhen Baoan Authentic TCM Therapy Hospital, Shenzhen, Guangdong 518101, PR China. Electronic address: cqh77@163.com.
  • Zeng XH; Affiliated Dongfeng Hospital, Hubei University of Medicine, Shiyan 442000, PR China; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, School of Pharmaceutical Sciences, Hubei University of Medicine, Hubei 442000, PR China. Electronic address: zengken@126.com.
Bioorg Med Chem Lett ; 30(23): 127554, 2020 12 01.
Article em En | MEDLINE | ID: mdl-32950616
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinonas / RNA Mensageiro / Neoplasias do Colo do Útero / Apoptose / Proliferação de Células / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinonas / RNA Mensageiro / Neoplasias do Colo do Útero / Apoptose / Proliferação de Células / Antineoplásicos Idioma: En Ano de publicação: 2020 Tipo de documento: Article